عباسعلي اميني

استادیار ایمنی شناسی پزشکی

اطلاعات تماس

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لینک سامانه علم سنجی

Abbas Ali Amini, Ph.D

 

 

Education

 

2009-2014

PhD. (Medical Immunology)  Thesis: Bioinformatics evaluation and in vitro construction of humanized vOX2-CD200:Fcg1 recombinant fusion protein and study of its anti-inflammatory effects in experimental models, Mashhad University of Medical Sciences, Mashhad, Iran

2005-2008

MSc. (Medical Immunology)  Thesis: Study of immunotherapy with Met-Enkephalin activated Tumor Infiltrated Lymphocytes in Fibrosarcoma-bearing Balb/C mice, Tehran University of Medical Sciences, Iran

2000-2005

BSc: Biology, Tabriz University, Tabriz, Iran

 

 

Appointments

 

2015- Now

Lecturer in Immunology, Kurdistan University of Medical Sciences (MUK)

 

Honors

2006

The second rank in the master's entrance exam for immunology in Iran

 

 

 

Professional services and Administrative positions

2019-now

Head of Immunology Department, School of Medicine; Kurdistan University of Medical Sciences, Sanandaj – Iran

2019-Now

Member of the Examiners Board in the Immunology Comprehensive Exam (Medicine, Pharmacy and Dentistry)

2017- Now

Head of Medical School Research Laboratories; Kurdistan University of Medical Sciences, Sanandaj – Iran

2017- Now

Member of committee in the Needs-Based Health Human Resources Planning; Kurdistan University of Medical Sciences, Sanandaj – Iran

2016- Now

 

Member of research committee in the Cellular and Molecular Research Center, Kurdistan University of Medical Sciences, Sanandaj – Iran

2016- Now

 

Member of research committee in the Cancer and Immunology Research Center, Kurdistan University of Medical Sciences, Sanandaj – Iran

 

Society membership

2006-now

Member of the Iranian Society of Immunology

 

Awards

2009

Tehran University of Medical Sciences (TUMS) Award for Innovative and Assiduous Student

2011

The best topic and lecture in the 7th Annual Research Congress of Eastern Medical Sciences Students, Mashhad University of Medical Sciences

2011

The best poster in 3d BuAli Research Festival, Mashhad University of Medical Sciences

 

Patents

2015

Optimization and construction of humanized vOX2-CD200:Fcg1 recombinant fusion protein as an anti-inflammatory agent  (Date and patent NO: 20/12/2015 - 87526)

 

 

Papers

  1. Mohsen Karbalaei Zadeh Babak, Mahboubeh Taghiabadi, SamanSoleimanpour, Masoud Saleh Moghad, Arman Mosavat, Abbas Ali Amini, Mohammad Ali Mohammad, Seyed Abdolrahim Rezaee. Mycobacterium tuberculosis Ag85b:hfcγ1 recombinant fusion protein as a selective receptor-dependent delivery system for antigen presentation. Microbial Pathogenesis, 2019 Apr; 129: 68-73. doi.org/10.1016/j.micpath.2019.01.045
  2. Ahmadi N, Ahmadi A, Kheirali E, Hossein Yadegari M, Bayat M, Shajiei A, Amini AA, Ashrafi S, Abolhassani M, Faezi S, Yazdanparast SA, Mahdavi M. Systemic infection with Candida Albicans in breast tumor bearing mice: Cytokines dysregulation and induction of regulatory T cells. J Mycol Med. 2019 Apr; 29(1):49-55. doi.org/10.1016/j.mycmed.2018.10.006
  3. Dariush Haghmorad, Zohreh Salehipour, Reza Nosratabadi, Maryam Rastin, Parviz Kokhaei, Mohammad Bagher Mahmoudi, Abbas Ali Amini and Mahmoud Mahmoudi. Medium-dose estrogen ameliorates experimental autoimmune encephalomyelitis in ovariectomized mice. J Immunotoxicol. 2016 Nov; 13(6):885-896.
  4. Saman Soleimanpour, Tahereh Hassannia, Mahdieh Motiee, Abbas Ali Amini & S. A. R. Rezaee. Fcγ1 fragment of IgG1 as a powerful affinity tag in recombinant Fc-fusion proteins: immunological, biochemical and therapeutic properties. Crit Rev Biotechnol. 2016 Apr 6:1-22.
  5. Maryam Mousavinezhad-Moghaddam, Abbas Ali Amin, Houshang Rafatpanah, and Seyed Abdol Rahim Rezaee. A new insight into viral proteins as Immunomodulatory therapeutic agents. KSHV vOX2 as a potent anti-inflammatory protein. Iran J Basic Med Sci. 2016 Jan; 19(1):2-13.
  6. Abbas Ali Amini, Alexandra S. Solovyova, Hamid Sadeghian, David J. Blackbourn, S.A. Rahim Rezaee. Structural properties of a viral orthologue of cellular CD200 protein: KSHV vOX2. Virology, 2015, 474, 94-104.
  7. Dariush Haghmorad, Abbas Ali Amini, Mohammad Bagher Mahmoudi, Maryam Rastin, Mahmoud Hosseini, and Mahmoud Mahmoudi. Pregnancy level of estrogen attenuates Experimental Autoimmune Encephalomyelitis in both ovariectomized and pregnant C57BL/6 mice through expansion of Treg and Th2 cells. Journal of Neuroimmunology, 2014, 277, 85-95.
  8. Marzieh Holakuyee, Mohammad Hossein Yadegari, Zuhair Mohammad Hassan, Mansour Bayat, Ariyo Shahin Jafari, Mohsen Abolhassani, Abbas Ali Amini, Mehdi Mahdavi. Candida albicans Structural and Secreted Proteins Modulate CD4/CD8 Ratio in Tumor Infiltrating Lymphocytes of Spontaneous Adenocarcinoma Bearing Mice. IJI, 2010, 7 (3), 142-149.
  9. Khosravi Ali Reza & Sohrabi Noushin & Hassan Zuhair & Mahdavi Mehdi & Amini Abbas Ali & Tebianian Majid & Shokri Hojjatollah & Ebrahimzadeh Mousavi Hoseinali. Evaluation of the expression of TLR-2, Dectin-1 and TNF-α level in invasive aspergillosis in cancer mice. Comp Clin Pathol. (2010).Volume 19, Number 6
  10. Amini Abbas Ali, Hajati Jamshid, Vodjgani Mohammad, Gheflati Zahra, Namdar Afshin, Holakovee Marzieh, Khansari Nemat. (2010). Study of Immunotherapy with Endogenous Opiod (Met-Enkephalin) Activated TILs in Fibrosarcoma Induced Balb/C Mice. Yakhteh Med J, 11(4): 408-417.
  11. Amari Afshin, Razavi S-Alireza, Jamali Arezoo, Ansaripour Bita, Amini Abbas Ali, Motamedi Masoumeh, Shojaei Saeideh. (2009) Effect of protein and DNA components of Toxoplasma gondii on IL-12 production from dendritic cells and T cell proliferation. Modares Journal of Med. Sci. 12(3): 1-8
  12. Amari A, Razavi AL, Jamali A, Amini AA, Motamedi M, Shojaee S, Ansaripour B, Pourgholaminejad A, Hadjati J. (2009). Effects of dendritic cell vaccine activated with protein components of toxoplasma gondii on tumor specific CD8+ T-cells. TUMJ, 67(9): 615-622.
  13. Nooshin Sohrabi, Ali Reza Khosravi, Zuhair Mohammad Hassan, Mehdi Mahdavi, Abbas Ali Amini, Majid Tebianian. Effect of Invasive Aspergillosis Infection on the Immune Responses of Cancer Mice. Iranian Journal of Basic Medical Sciences Vol. 11, No. 4, 2009, 242-249.

 

 

National (Iranian) seminar invitations

2011

Speaker; Protein Modeling and Reverse Engineering Workshop. The 7th annual research congress of eastern medical sciences students; Mashhad, Iran

2011

Speaker; Flow Cytometry Workshop. The 7th annual research congress of eastern medical sciences students; Mashhad, Iran

 

National Congresses

 

  1. Amini AA, Blackbourn DJ, Rezaee AR. Structural studies of KSHV vOX2, a viral orthologue of cellular CD200. The 12th Iranian International Congress of Immunology and Allergy. 2014; April 29th to May 2nd, Tehran, Iran; (Poster).
  2. Rezaee SA, Rafatpanah H, Pourseyed SH, Amini AA, Assarehzadegan M. Quantification of HTLV- I proviral load in different organs of BALB ⁄c mice by Real–Time PCR. The 12th Iranian International Congress of Immunology and Allergy. 2014; April 29th to May 2nd, Tehran, Iran; (Poster).
  3. Amini A.A, Sadeghian H, Rafatpanah H, Rezaee S.A.R. 3-Dimentional molecular modeling studies of KSHV vOX2 protein as an example of Immuno-Regulatory molecule. The 11th Iranian International Congress of Immunology and Allergy. 2012; April, 26-29, Tehran, Iran; (Oral).
  4. Haghmorad D, Mahmoudi M.B, Amini A.A, Tabasi N, Hosseini S.M, Khakzad MR, Zamani Taghizadeh Rabe S, Soltani S, Rastin M, Mahmoudi M. Gold nanoparticles ameliorates experimental autoimmune encephalomyelitis in C57BL/6 mice. The 11th Iranian International Congress of Immunology and Allergy. 2012; April, 26-29, Tehran, Iran; (Poster).
  1. Mahmoudi M.B, Haghmorad D, Amini A.A, Tabasi N, Zamani Taghizadeh Rabe S, Rastin M, Hosseini S.M, Mahmoudi M. 1,25-dihydroxyvitamin D3 ameliorates experimental autoimmune encephalomyelitis in C57BL/6 mice. The 11th Iranian International Congress of Immunology and Allergy. 2012; April, 26-29, Tehran, Iran; (Poster).
  2. Haghmorad D, Amini A.A, Mahmoudi M.B, Hosseini S.M, Tabasi N, Soltani S, Zamani Taghizadeh Rabe S, Rastin M, Mahmoudi M. Anti-inflammatory properties of Thymoquinone alleviate experimental autoimmune encephalomyelitis in C57BL/6 mice. The 11th Iranian International Congress of Immunology and Allergy. 2012; April, 26-29, Tehran, Iran; (Poster).
  1. Sohrabi N, Hassan Z.M, Khosravi A, Mahmoudi M, Amini A.A, Tebianian M. Disseminated infection with Aspergillus Fumigatus enhanced tumor growth and severity in tumor bearing mice model. The 11th Iranian International Congress of Immunology and Allergy. 2012; April, 26-29, Tehran, Iran; (Poster).
  2. Maryam Rastin, Nafise Tabasi, Darioush Haghmorad, Abbas Ali Amini, Samane Soltani, Mitra Masoudian, Mahmoud Mahmoudi. Immunomodulatory effects of 1,25 dihydroxyvitamin D3 on SLE patients. 12th Iranian Congress of Biochemistry & 4th International Congress of Biochemistry and Molecular Biology, 2011; September 6-9; Mashhad, Iran; (Poster).
  3. Amini Abbas Ali, Haghmorad Dariush, Hoseini Mahmoud, Jalayer Zoleikha, Masoudian Mitra, Zamani Shahrzad, Rastin Maryam, Mahmoud Mahmoudi. Effect of hespiridin on experimental autoimmune encephalomyelitis in C57BL/6 mice. 12th Iranian Congress of Biochemistry & 4th International Congress of Biochemistry and Molecular Biology. 2011; September 6-9, Mashhad, Iran; (E-Poster).
  4. Haghmorad Dariush, Amini Abbas Ali, Mahmoudi Mohammad Bagher, Soltani Samaneh, Rastin Maryam, Hosseini Mahmoud Mahmoudi. Effects of estrogen on experimental autoimmune encephalomyelitis in C57BL/6 Ovariectomized mice. 12th Iranian Congress of Biochemistry & 4th International Congress of Biochemistry and Molecular Biology. 2011; September 6-9, Mashhad, Iran; (E-Poster).
  5. Abbas Ali Amini, Dariush Haghmorad, Mitra Masoudian, Shahrzad Zamani, Nafise Tabasi, Maryam Rastin, Mahmoud Mahmoudi. Immune response profile in estrogen treated ovariectomized experimental autoimmune encephalomyelitis induced mice. 12th Iranian Congress of Biochemistry & 4th International Congress of Biochemistry and Molecular Biology. 2011; September 6-9, Mashhad, Iran; (E-Poster).
  6. Abbas Ali Amini, Jamshid Hadjati, Zahra Gheflati, Nemat Khansari. Study of immunotherapy with Met-Enkphalin activated Tumor Infiltrated Lymphocytes in Fibrosarcoma-bearing Balb/C mice. The 9th Iranian International Congress of Immunology and Allergy. 2008, June 18-20, Tehran, Iran; (Poster).
  7. Abbas Ali Amini, Jamshid Hadjati, Zahra Gheflati, Nemat Khansari. Immune response profile in mice treated with Met-Enkphalin activated Tumor Infiltrated Lymphocytes. The 9th Iranian International Congress of Immunology and Allergy. 2008, June 18-20, Tehran, Iran; (Poster).